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Pediatric Inpatient, Critical Care and Emergency Research


Pediatric intensivist Dr. Anupam Sehgal and general pediatrician Dr. Anne Moffatt collaborate with investigators from pediatric departments across Canada to strengthen research evidence through membership in the Paediatric Inpatient Research Network (PIRN), the Canadian Critical Care Trials Group (CCCTG) Pediatric Interest Group, and Pediatric Emergency Research Canada (PERC). They are involved as co-investigators in the following multi-centre studies:

  • Patient-oriented Research Priorities for Pediatric Hospital Care: A James Lind Alliance Priority Setting Partnership
  • PRoMPT BOLUS: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis
  • Precision Medicine for Improving the Diagnosis of Pediatric Appendicitis in the Emergency Department (PRIMED) study
  • COVID-19 surveillance study
  • Impact of restricted visitation policies during the COVID-19 pandemic on parents of critically ill children
  • Care and outcomes of Canadian children hospitalized with periorbital and orbital cellulitis

In addition, Dr. Sehgal is currently leading a study of treatment adherence to seizure management of children and youth presenting to the emergency departments of two general hospitals (supported by a grant from the Clinical Teachers’ Association of Queen’s (CTAQ) Research Endowment Fund). He and Lakshmi Subramanian (Pediatrics resident) are co-principal investigators on a study that seeks to answer the question "How common are eating disorders in individuals with immune-mediated gastrointestinal diseases?" using ICES data. This project is supported by a grant from the SEAMO Innovation Fund. Pediatric co-investigators include Dr. Amy Acker and Dr. Dan Mulder.

Our department also contributes data to the International Kawasaki Disease Registry and is a participating site in a study examining the association of Kawasaki Disease and COVID-19 with cardiac complications.